Patients with type 2 diabetes who are taking the drug Invokana (canagliflozin) should be particularly cautious about symptoms that may seem like standard side effects. THEY COULD BE A WARNING FOR SOMETHING MUCH WORSE.
When taking Invokana, nausea, and vomiting, difficulty breathing, abdominal pain, confusion, and unusual fatigue may signal a dangerous condition called diabetic ketoacidosis (DKA), which can lead to hospitalization, coma, and even death.
The FDA recently issued a safety communication warning both patients and doctors about the risk and stating they are investigating the issue to determine if they need to make changes to the prescribing information for the drug.
FDA Warning Regarding Invokana Ketoacidosis
Invokana has been on the market since March of 2013 when the FDA approved it for the treatment of type 2 diabetes. It is one of a new class of drugs called “sodium-glucose co-transporter 2 (SGLT2) inhibitors.
SGLT2 inhibitors work to lower blood sugar levels by actually inhibiting the kidneys from absorbing glucose, which causes more of it to be flushed out of the body through urine. Other medications in the same class as Invokana include Farxiga, Glyxambi, Jardiance, and Xigduo XR.
Increased Risk Of Diabetic Ketoacidosis
On May 15, 2015, the FDA warned that these drugs could increase the risk of DKA, a condition in which the body produces too many “ketones.”
The condition is often a sign that there is not enough insulin for the body to draw adequate glucose from the blood into the cells, so it turns to fat instead. This is only a problem if high levels of ketones accumulate in the blood—which causes it to become too acidic.
While patients with Type 1 diabetes are typically more at risk for DKA than patients with type 2, The drug, Invokana is putting those with type 2 at a higher risk.
The FDA became alarmed when they received 20 reports of patients with type 2 diabetes suffering DKA. The connection came when it was reported that the 20 patients were also taking SGLT2 inhibitors.
DKA can lead to serious complications, including:
• Cerebral edema
Invokana Attorneys Advise You To Look For Side Effects
DKA is only one of many potential side effects associated with Invokana. Within just a year of its release, the medication was linked with 457 reports of problems. According to the Institute for Safe Medication Practices (ISMP) QuarterWatch report, these included:
- Kidney failure or impairment
• Dehydration and fluid imbalances
• Kidney stones
• Urinary tract infections
• Allergic reactions
• Abnormal or other weight loss
Some doctors are also concerned about the long-term effects of the drugs on the kidneys. The FDA noted in their review that the long-term consequences of canagliflozin on the kidneys were unknown and that it was “prudent to assume” that the slightly reduced kidney function seen in the studies “places patients at increased risk for clinically significant episodes of acute kidney injury.”
St. Louis Invokana Lawyers Are Here To Help!
If you or a loved one suffered ketoacidosis, cardiovascular problems, urinary tract infections, or other serious injuries after taking Invokana contact Schultz & Myers Personal Injury Lawyers as soon as possible.
Our dangerous drug attorneys are trained in investigating injuries that stem from the negligence of a company or manufacturer. We know firsthand how quickly the medical bills can pile up, and we’re here to help.